〖研究经历〗：
主要从事分子酶工程与发酵工程等相关研究。主持863计划课题、973计划课题、国家自然科学基金和十一五支撑计划等国家级课题8项，主持江苏省高技术研究计划省部级课题1项，主持纵向经费共计1080万元.
代表性科研项目如下：
1. “食品酶及其应用” 863重点项目，编号：2012AA022207
2. “脂肪酶的分子改造与分子催化机制研究” 973课题，编号：2011CB710802，
3. “L-薄荷醇生物拆分用酶的分子改造与高效制备关键技术研究” 国家高技术研究发展计划“863”项目，编号：2008AA10Z304
4. “基于酶活力指纹图谱的微生物脂肪酶酯合成反应规律的研究”，国家自然科学基金，编号：20802027
5. “工业酶的分子改造和工程化技术”，国家高技术研究发展计划“863”重点项目，编号：2006AA020202
6. “酶制剂及生物催化关键技术产业化”, 国家十一五支撑计划，编号：2008BAI63B07
〖主要论著〗（著作和论文）：
1. Xiao-Wei Yu, Chong Sha, Yong-Liang Guo, Rong Xiao, Yan Xu, High-level expression and characterization of a chimeric lipase fromRhizopus oryzae for biodiesel production, (2013) Biotechnology for Biofuels 6:29 (IF 5.5)
2. Xiao-Wei Yu, Xin Lu, Lin-Shui Zhao, Yan Xu. Impact of NH4+nitrogen source on the production of Rhizopus oryzae lipase in Pichia pastoris. Process Biochemistry 48 (2013) 1462-1468 (IF 2.4)
3. Xiao-Wei Yu, Nian-Jiang Tan, Rong Xiao, Yan Xu, Engineering a Disulfide Bond in the Lid Hinge Region of Rhizopus chinensis Lipase: Increased Thermostability and Altered Acyl Chain Length Specificity. (2012) PLoS One 7(10):e46388 (IF 4.1)
4. Xiao-Wei Yu, Rui Wang, Yan Xu, Rong Xiao and Meng Zhang, Enhanced thermostability of a Rhizopus chinensis lipase by in vivorecombine tion in Pichia pastoris. (2012) Microbial Cell Factories11:102-112 (IF 3.5)
5. Xiao-Wei Yu, Yan Xu, Hong Gu. Enhancement of chiral resolution of dl-menthol at high substrate concentration by in situ resin adsorption. (2010) Journal of biotechnology 150:S345 (IF 3.0)
6. Xiao-Wei Yu, Yan Xu, Rui Wang.Enhancement of activity of Rhizopus chinensis lipase by directed evolution. (2010) Journal of biotechnology 150:S344 (IF 3.0)
7. Xiao-Wei Yu, Le-Le Wang, Yan Xu. Rhizopus chinensis lipase: gene cloning, expression in Pichia pastoris and properties. (2009)Journal of Molecular Catalysis B: Enzymatic 57:304-311 (IF2.7)
8. Xiao-Wei Yu,Yong-Quan Li. Kinetics and thermodynamics of esterification of propyl gallate by mycelium-bound tannase in organic solvent. (2006) Journal of Molecular Catalysis. B, Enzymatic 40:44-50 (IF 2.7)
9. Xiao-Wei Yu, Yong-Quan Li, Dan Wu. Enzymatic synthesis of gallic acid esters using microencapsulated tannase: effect of organic solvents and enzyme specificity. (2004) Journal of Molecular Catalysis. B, Enzymatic 30:69-73 (IF 2.7)
